Lipidomics of Alzheimer's Disease
Publisher:
Nature Neuroscience Date published:
20 October, 2008Region:
International Publication type:
researchPublication link:
Lipidomics of Alzheimer's DiseaseThe role fatty acids play in Alzheimer's Disease (AD) is unclear. Sanchez-Mejia et al. identified increased arachadonic acid levels in a mouse model for AD, resulting from amyloid-beta activation of phospholipase A2 (GIVA-PLA2). Inhibiting GIVA-PLA2 protected against amyloid-beta-induced toxicity and deficits in learning and memory.
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