Executive Summary: EPR, Oxidative Stress and Ageing
Publisher:
SparcDate published:
23 May, 2008Region:
United Kingdom Publication type:
researchPublication link:
Executive Summary: EPR, Oxidative Stress and Ageing General Poster: Oxidative Stress & Ageing
Cells age for many reasons. They can be damaged by radicals, particularly oxygen-centred radicals causing pathologies such as arterioscelerosis, neoplasma and cataracts and play a role in stroke, neurodegeneration and autoimmune diseases. Understanding the biological sources of radicals, their behaviour in different environments and the cellular responses to them is a key to understanding the ageing process and ameliorating the diseases of old age. The study will develop new techniques using EPR spectroscopy for detecting radicals at the sites where they cause most damage.
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